Plaque stabilisation by systemic and local drug administration
نویسندگان
چکیده
منابع مشابه
Atherosclerotic plaque rupture: local or systemic process?
It is generally established that the unstable plaque is the major cause of acute clinical sequelae of atherosclerosis. Unfortunately, terms indicating lesions prone to plaque instability, such as "vulnerable plaque," and the different phenotypes of unstable plaques, such as plaque rupture, plaque fissuring, intraplaque hemorrhage, and erosion, are often used interchangeably. Moreover, the diffe...
متن کاملApproach / Drug Dosage Administration Plaque Site Main Findings in Plaques
High-density lipoproteins (HDL) are typically defined as lipoprotein particles with buoyant densities from 1.063 to 1.21 g/mL and having apolipoprotein AI (apoAI) as the major apolipoprotein species. It has become increasingly appreciated that the HDL population consists of a collection of particles with diverse sizes, structures, and composition and functional properties that are thought to in...
متن کامل/ Drug Dosage Administration Plaque Site Main Findings in Plaques
High-density lipoproteins (HDL) are typically defined as lipoprotein particles with buoyant densities from 1.063 to 1.21 g/mL and having apolipoprotein AI (apoAI) as the major apolipoprotein species. It has become increasingly appreciated that the HDL population consists of a collection of particles with diverse sizes, structures, and composition and functional properties that are thought to in...
متن کاملPrevention of Intraabdominal Adhesions by Local and Systemic Administration of Immunosuppressive Drugs
BACKGROUND Intraperitoneal adhesion formation is a serious postsurgical issue. Adhesions develop after damage to the peritoneum by surgery, irradiation, infection or trauma. OBJECTIVES Using a rat model, we compared the effectiveness of systemic and intraperitoneally administered common immunosuppressive drugs for prevention of postoperative intraperitoneal adhesions. MATERIALS AND METHODS ...
متن کاملIntraocular concentrations of chemotherapeutic agents after systemic or local administration.
OBJECTIVES To investigate the concentrations of carboplatin and etoposide achieved in the aqueous and vitreous humors after intravenous infusion in nonhuman primates, and to investigate whether local administration of carboplatin might result in higher concentrations in the vitreous humor. METHODS Macaca fascicularis primates were treated with 1 of 3 regimens: (1) intravenous carboplatin (18....
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ژورنال
عنوان ژورنال: Heart
سال: 2004
ISSN: 1355-6037
DOI: 10.1136/hrt.2004.034975